Sunday, May 30, 2021

Corona Daily 077: Overjoyed in Ohio


Abbigail Bugenske, a 22-year old freshly employed engineer, was driving from Cincinnati to her parents’ house near Cleveland. It was the evening of Wednesday, 26 May. She switched to hands-free when her phone rang.

“Hi, is that Abbigail?” asked a mature voice. “This is Mike DeWine – the governor of Ohio.”

Abbigail knew who Mike DeWine was. But there was no way the governor was going to call her. She focused on the voice to see if it was any of her friends. The voice kept talking. He said he was making the call on live TV. The whole town, the entire state of Ohio was listening to the conversation. Was she watching TV? Abbigail said no, sorry, she was driving. Fortunately, she had almost reached her parents’ house by the time the call ended. It was just after 7.30 pm.

*****

Abbigail was screaming when she entered the house. Her parents rushed out thinking she was crying. Something was wrong.

“Mike DeWine, the governor just called me,” Abbigail said, “I won $1 million. I am going to be a millionaire.”

Her father grabbed her by the shoulders. “Calm down,” he said. “What the hell are you talking about?”

The talk was interrupted by Abbigail’s phone. She was getting thousands of new followers on Instagram and Facebook. The messages continued non-stop. Friends and strangers congratulating her on winning Ohio’s Vax-a-million lottery.

*****

In another part of Ohio, Colleen Costello, a chemical engineer was leaving the office when the same Mike DeWine called her. Colleen thought she was listening to the governor’s taped message. The more they talked, the more she realized it was really him, live. Colleen was thankful there was a bench nearby for her to sit down. The call over, she dialed her husband, and asked him if he was sitting down. He hurried to pick up their 14 year old son, Joseph, from youth group. They rode home, their hearts beating wildly.

As promised, on the lawn of their house; the governor himself, his wife and the governor’s staff were waiting for them.

*****

In the USA, the vaccine supply now far exceeds demand. It is becoming difficult to get people to the vaccination centers. In some states, free transport from home is arranged. There are people who won’t take vaccines no matter what. There are others who want to wait for a few months to see what impact vaccines have on the others.

In brainstorming sessions, the Ohio governor liked the idea of a vaccine lottery. Anyone taking even a single shot can enter it, and every week, Ohio will give the winner $1 million. Abbigail Bugenske was the first winner.

As part of the same initiative, a vaccinated teenager would be picked up randomly. His entire four years’ college education, tuition fees, accommodation, textbooks and all education related expenses would be borne by the State. This four year full-ride scholarship lottery was won by 14 year old Joseph Costello. While Abbigail had taken her vaccine before the lottery was announced, Joseph was vaccinated only last Saturday, with the lottery announcement crossing his mother’s mind when she registered his name.

*****

If you live in Ohio, you have four more Wednesdays. June will turn four more lucky winners into instant $millionaires. Parents of four more chance youngsters would be relieved to know they don’t need to spend on the child’s university education.

American states are competing to entice Americans. Memphis will give a new car. Maryland and Oregon have launched their own lotteries. Kentucky is handing over 225,000 free lottery tickets. Maine will give 10,000 licenses for hunting and fishing. Not to be left behind, California, on 15 June will pay $1.5 million each to ten randomly selected vaccinated people.

*****

Offering millions of dollars and cars to bribe the people to get vaccines is happening in the same mystifying world, at the same time, where billions are desperate to get access to vaccines, some of them are on ventilators, others dying.

No vaccine has been invented for the man-made virus called inequality.

Ravi 

Saturday, May 29, 2021

Corona Daily 078: Chinese Lab Leak Theory: Part Final


Eighteen months after its birth, there appears to be a consensus among scientists that the origin of covid-19 virus was the horseshoe bat. The virus spilled over into humans either directly, or more likely via another animal. The genome analysis suggests it could be a cross between a bat virus and say a pangolin virus, with some additional genetic sequence (called furin cleavage site) that makes it far more infectious for humans.

Such blending and spicing up can be done in labs. In 2015, Dr Shi’s team from WIV created a chimera from a bat coronavirus and a mouse coronavirus that was able to replicate efficiently in human airway cells. Those suspecting a lab leak suggest the engineering of the furin cleavage site could have been the product of WIV.

However, most scientists believe such engineering is more likely to happen in nature. Nature is the greatest designer.

The lab leak theory neither insists on a Wuhan lab designing the covid-19 virus, nor deliberately using it as a bio-weapon. The naturally created virus could accidentally slip from a lab through negligence, accident or sheer bad luck. Crashing of a Petri dish is not required. An infected bat, brought in for research, can transmit the virus to a lab employee, and start a global pandemic.

*****

In this mystery, where millions are killed, certain suppression of data raises doubts. China has the key epidemiological data on the first 174 covid patients in December 2019. The authorities refused to share it with the WHO delegation. Such data is critical for investigation, and can clearly tilt the balance towards one of the hypotheses.

China is in a difficult situation. If they keep the data secret, they will be assumed guilty. If they share it, who knows what will come out.

They have instead opted for whataboutism. A hawkish Chinese ministry spokesman has demanded the USA opens up its Fort Detrick (a US lab established to develop bio-weapons in the past, now runs a biological defence program) for international scrutiny. The biologist Dr Daszak reminds us that China is a sovereign country. Why should it open up its lab records to outsiders? Daszak must ask the coronavirus if it is aware of the concept of a country’s sovereignty.

*****

The stated objective of the virus re-engineering research (gain of function) was to prevent pandemics. The irony is that such research has not prevented, but may have caused the pandemic. Neither did the WIV manage to create covid medicines or vaccines as promised in its agenda.

Countries are now competing for virology research. There is no global authority or international treaty that sanctions such labs. USA already has more than a dozen BSL-4 labs, and more are planned. After the pandemic, more scientists will be keen to research dangerous viruses. That will mean more researchers going to the caves, coming into contact with BATS and other animal reservoirs of viruses, collecting samples, working on them in labs, upgrading them to make them potent killers, and in this entire process leaking them through accident or negligence.

The existence of such viruses is itself a major threat. Despite repeated requests to destroy them, a collection of live smallpox viruses is stubbornly held at Koltsovo (Russia), and Atlanta (USA). It just needs a single madman to use them. Both USA and Russia have shown capability of having madmen at the helm.

China should use this as a negotiation tool. To open up their records, they can insist on an international audit of all such labs in the world. That would be fair. Any lab leak can start another pandemic. An international treaty exercising strict controls and scrutiny over all bio-labs is essential. As critical as control over nuclear installations. Pandemics may be a greater threat than nuclear warfare. In the name of science, researchers can’t make the world a more vulnerable place. The gain of function research to make natural viruses more vicious should be banned. The smallpox viruses in Russia and USA must be destroyed.  

If such bargaining results in worldwide bio-safety lab reforms, China may be forgiven even if the lab leak theory proves correct.

Ravi 

Friday, May 28, 2021

Corona Daily 079: Chinese Lab Leak Theory: Part Four


Smallpox, Ebola, plague, SARS are dangerous viruses, and for scientists to conduct research on them, the lab must have a specified BioSafety Level (BSL). The levels of containment range from BSL-1, the lowest to BSL-4, the highest. The world has fewer than fifty BSL-4 labs; China has two, the Wuhan Institute of Virology being one.

All BSL-4 researchers must change clothes at entry, shower upon exiting, and decontaminate all the materials used during experiments. The lab itself must be in a separate building or wing, with its own air filtration and decontamination systems.

Working in astronaut suits, the researchers can’t have coffee or feel hungry. The negative air flow dehydrates and exhausts them. Working longer than three hours at a stretch is difficult. Wearing that suit and having a runny nose is a nightmare. If you sneeze, you can’t clean your face shield.

Equipment breaking is another problem. The lab must turn everything off, remove the equipment from the BSL-4 lab, and decontaminate it before fixing it. The Wuhan lab cost $44 million, and was the first Chinese lab approved as BSL-4 in 2015.

*****

Such precautions are important, because pathogens manage to escape frequently. The last smallpox death was a result of a lab leak in the UK in 1978. The original SARS escaped twice, once in Singapore, once in Taiwan. In 2004, SARS leaked out of a Beijing lab twice. In December 2019, around the same time as covid-19 started, more than 100 students at two agricultural research centers in Lanzhou in Northwest China were infected with brucellosis, a bacteria transmitted by livestock.

American diplomats who visited the Wuhan Institute of Virology in 2018 specifically mentioned coronavirus and the pandemic risk. In February 2020, China issued new rules requiring labs to increase their biosafety, suggesting there was something to improve.

*****

In February 2020, Botao Xiao and Lei Xiao, two Chinese scientists published a paper “the possible origins of 2019-nCoV coronavirus”.

They screened the area around the seafood market and found two labs conducting research on coronavirus. Wuhan CDC lab was within 280 meters from the market. In one study, the lab researchers had captured 605 bats. The expert who collected them was aware of the danger of proximity to bats. He quarantined for 14 days each on two occasions, once when a bat attacked him, and once when the bat peed on him.

Surgery was performed on the caged animals, tissue samples were collected for analysis. Tissue samples and contaminated trash were a source of pathogens. This center was next to the Union hospital, where the first group of doctors was infected.

In summary, the researchers say the killer coronavirus probably originated from a laboratory in Wuhan.

Not surprisingly, the Xiaos were asked to withdraw the study. (Fortunately, the paper is still available). “The speculation was based on published papers and media and not supported by direct proofs.” Said Botao Xiao in an interview.

*****  

The Xiao paper was withdrawn under government pressure before it was peer-reviewed. But the WHO report in March 2021 is an official document. In projecting the hypothesis, the report says: …although rare, laboratory accidents do happen… humans could become infected in laboratories with limited biosafety, poor laboratory management practice or following negligence.

This is followed by an interesting paragraph: “The Wuhan CDC laboratory moved on 2 December 2019 to a new location near the Huanan market. Such moves can be disruptive for the operations of any laboratory.”

If you have moved houses, you know what a nightmare moving is. And to move a bio-safe facility handling 605 bats, it may be more so. This is the same lab the Chinese researchers mention in their paper. For reasons best known to WHO, the biosafety level of the Wuhan CDC is not mentioned in the report. It is BSL-2.

Shi Zhengli may have spoken the truth saying nothing leaked from her institute. What about the other Wuhan labs, particularly the one that moved on 2 December 2019?

*****                                                                                                                                                             

Based on the data available so far, I will sum the case up tomorrow.

Ravi 

Thursday, May 27, 2021

Corona Daily 080: Chinese Lab Leak Theory: Part Three


Suddenly the lab leak theory is in headlines everywhere, particularly in nations where life is becoming normal.

Yesterday, President Biden, speaking publicly, asked the US intelligence agencies to redouble their efforts to find the truth. He has given them 90 days to come back with a report.

Before that, on 14 May, eighteen scientists published a letter in a scientific journal urging further investigations into the origins of Covid-19. The WHO visit in March, and the delegation including the ever-present Dr Daszak, a man with conflicting interests; produced a report that did not satisfy anyone. The two theories were not given balanced consideration, with only 4 out of the report’s 333 pages talking about the possibility of a lab accident. The scientists now demand an investigation that is transparent, objective, data-driven, inclusive of broad expertise, subject to an independent oversight, and responsibly managed to minimize the impact of conflicts of interest. (Meaning all these factors were absent during the WHO visit).  

Taking cue, Facebook today lifted a year-long ban. From now on, your FB posts can say the virus was man-made. Earlier, this was considered misinformation that warranted removal of the post.

One possible reason for the revival of the subject is the World Health Assembly, which meets this week (24 May-1 June), virtually. This is a decision making body of the WHO. The theme of its weekly conference is: “Ending this pandemic, preventing the next: Building together a healthier, safer and fairer world.”

Of course, if the world knew how the current pandemic started, that will be a big help in preventing the next one.

*****  

If prosecution (led by the USA) must present evidence to show the coronavirus leaked from a lab, the defense (China) can strengthen its argument by offering evidence of a natural spillover from animal to human.

Scientists have been skeptical of the lab leak theory because animal spillover has been common in most epidemics. Genetics studies show that nearly every disease mankind has faced has jumped from animals: bubonic plague from rats, measles likely from cows, whooping cough from dogs, and AIDS from Chimpanzees.  

SARS virus was transmitted to humans from civets and MERS from dromedary (Arabic) camels. This detection happened within four months for SARS and nine months for MERS. Now, eighteen months after the start of Covid-19, scientists have failed to discover an intermediary who has passed on the covid virus to humans.

*****

The bats blamed as the source live in Yunnan or Zhejiang province, both provinces nearly 1000 km away from Wuhan’s seafood market. Bats normally live in caves and trees and are not known to fly 1000 km to reach a densely populated town of 15 million. Research among Wuhan residents showed bats are neither eaten in Wuhan nor traded at its markets. If bats were a source, an intermediate host was essential. Pangolin was suggested in the beginning, but for want of evidence nobody is talking about it now.

The Wuhan Institute of Virology is the premier virology institute not only in China, it ranks among the top in the world. How did the coronavirus originating from bats located 1000 km away decide to infect people precisely in the town where China’s premier Virology institute is situated? Why did the epidemic not start in places between Yunnan and Wuhan? One possibility is that people in other places were infected, but because of top-class virologists, Wuhan managed to detect the virus first. (Like UK’s superior genomic surveillance ability allowed it to quickly find mutations). But the studies conducted in other Chinese towns/villages did not show any presence of antibodies outside Wuhan.

*****

None of this discussion suggests Bats were not the source, they probably were. Nor that the coronavirus was not natural, it could be. Still China in its defense must map out the route of the virus from the Yunnan caves to Wuhan. Its failure to do so makes the virus landing precisely in Wuhan a spooky coincidence. The logical alternative is that the virus existed in a Wuhan lab, and accidentally went out. More on that, tomorrow.

Ravi   

Wednesday, May 26, 2021

Corona Daily 081: Chinese Lab Leak Theory: Part Two


In this debate of natural spillover vs lab leak, it is critical to understand a term “Gain of Function Research.”

In virology, this research is done with the intention of better forecasting future pandemics and developing solutions to them. Scientists take a virus, usually known to endanger humans, and start tweaking it to make it more transmissible or more lethal. This is a dangerous game. The idea is to develop in the laboratory viruses that may start deadly pandemics in the future, so as to develop medicines and vaccines in advance.

Scientists who support such research argue this is the only way to stay ahead of the epidemics. New diseases emerge all the time and viruses keep evolving. This research allows the world to stockpile vaccines and antibodies.

The opponents agree this objective may be noble, but the research is capable of building Frankensteins. Robert Oppenheimer, the father of the atomic bomb, and Albert Einstein, the greatest theoretical physicist, were scientists and professors. In their scientific endevour, they probably didn’t plan to drop nuclear bombs on Hiroshima and Nagasaki – but that is what happened in the end.

The troubling thing is that the Wuhan laboratories routinely create viruses more dangerous than those existing in nature. The Chinese don’t deny those man-made mutations. They argue they can do it safely, and stay ahead of nature in the game. Dr Shi Zhengli, the Chinese Batwoman, and her team has done work on inserting cleavage sites into viruses to check if that enhanced their ability to infect humans.

Such man-made viruses are called Chimera viruses. Combining two pathogenic viruses increases the lethality of the new virus. That is why Chimeric viruses are generally considered a bio-weapon. The USSR had secretly tried combining encephalitis and small pox, and later Ebola and smallpox.

There have been cases of lab leaks before. But most have infected and killed very few people. Scientists believe that the annual H1N1 flu (1977-2009) was the result of a leak. The strain first appeared in Eastern Russia, and its genes were identical to a 1950 strain that was presumably stored in a Russian freezer for 27 years. The virus behaved as if it was deliberately weakened. The assumption is that Russian virologists were trying to develop a vaccine against the return of the 1918 flu.

*****

Having established that the Wuhan scientists have worked on developing Chimera viruses, let us now go through all the evidence that has emerged so far.

On 23 May, the Wall Street Journal published a report that three researchers from Wuhan Institute of Virology had become sick and were hospitalized in November 2019. Their symptoms were consistent with both Covid-19 and common seasonal illnesses. This is part of the US intelligence report that was not previously disclosed.

Shi Zhengli and the Chinese government have denied anybody from the institute was ill. So, it is the American word against the Chinese word. We live in a world where it is difficult to trust any government. If US intelligence really had any evidence, it is impossible that Donald Trump would have let it go. Unless more specific evidence is produced, it is difficult to take the WSJ report as proof of anything.

*****  

On 19 February 2020, a group of public health scientists had issued a statement in the Lancet in support of the Chinese scientists. It strongly condemned conspiracy theories that covid-19 doesn’t have a natural origin. Genome analysis, the statement said, overwhelmingly concludes that the coronavirus originated in wildlife.

One of the authors was Peter Daszak, a British zoologist and president of the EcoHealth Alliance in New York. Now it turns out that the letter was organized and drafted by him. Dr Daszak’s organization funded coronavirus research at the Wuhan Institute of Virology. If the covid virus really leaked from the research he financed, he may be held potentially guilty. Dr Daszak pro-actively hid this conflict of interest. The lancet letter ends with: “We declare no competing interests”.

*****

(Story continued tomorrow)

Ravi 

Tuesday, May 25, 2021

Corona Daily 082: Chinese Lab Leak Theory: Part One


In January 2020, from what we read in the news, the coronavirus first appeared at Wuhan’s Huanan seafood market. Wet markets around the world are literally wet because of live fish splashing in tubs of water, melting ice to keep meat cold and the blood and organs of slaughtered animals.

Wuhan’s market was not only a wet market, but a wildlife market. It sold exotic live and killed species: snakes, beavers, porcupines, baby crocodiles and others that people in other continents would not imagine eating.

The non-vegetarian food in Europe, USA or India is usually made from animals that are themselves largely vegetarian: cow, lamb, duck, chicken. Chinese, on the other hand, can eat carnivores. Some people wondered if this could be the cause of the virus appearing at the market. It is true that wildlife and human life should have some distance from one another, to prevent a virus spillover. In the beginning of 2020, the world demanded that China should shut its wildlife markets.

One question made me uneasy. Why now? Chinese people have been eating wild animals for over 1000 years. Earlier, China was extremely poor. For survival, they had to eat whatever moved on four legs. After developing a taste for centuries, the habit continued even for well-off Chinese. If the Chinese have been buying exotic animals for centuries and eating them, why should that cause a pandemic now?

*****

Trump called it the Chinese virus. Conspiracy theorists said this was China’s bio-weapon to become the ultimate superpower. Scientists analyzing the DNA of the virus said it was a natural virus, not made in any lab.

Now eighteen months later, more information is available. Last week, 18 leading biologists have published a letter calling for a new investigation. Once again the Chinese Lab Leak theory is in the news, big time.

It is like a murder mystery where only circumstantial evidence is available. The balance of probabilities can help us form a judgment.

*****

The four possibilities discussed last year were:

(a)  Natural: From the Wuhan seafood market or somewhere else. A few infected Chinese patients at the beginning of the pandemic had nothing to do with the seafood market. It is possible the food from the market reached and infected them. However, it is increasingly accepted the seafood market was not the primary source.

(b) Regular scientific work, but bad safety: The Wuhan lab may have been researching tests or vaccines, which is a legitimate activity. Accidentally, a breach caused the leak.

(c)  Bad intentions, and bad safety: Chinese scientists were trying to create an engineered bio-weapon. Just like nations developing nuclear weapons, without planning to use them. Sadly, an accidental leak occurred.

(d) China deliberately released the covid virus: This theory is considered unlikely. If it was deliberate, China didn’t need to launch the weapon in its own territory.

*****

In late December 2019, doctors at hospitals near Wuhan’s Huanan seafood market began seeing patients with a strange viral pneumonia. On 30 December, the Wuhan Municipal Health commission issued a warning. On the following day, WHO put out a global alert.

On 1 January, the Huanan seafood market was closed and hosed down with water. This was a crime scene that might have contained clues. Before the market closure, sellers were driven away with their animals. Some sellers may have had infected animals. Some live animals or fresh meat may have gone to other markets or in the trash. Customers left the market. And then the hosepipes cleaned it. The best epidemiological evidence was probably lost.

The Chinese health commissions then ordered diagnostic and genetic labs to destroy the samples of viruses they held, or pass them to the high level biosecurity lab. Most labs burned them. This was cited as a cover-up by the Trump administration. However, this is a standard safety procedure to prevent an outbreak. In 2014, CDC USA had given a similar order when Ebola was detected.

*****

(Continued tomorrow) 

Monday, May 24, 2021

Corona Daily 083: Father of Social Distancing


Sanitary measures described include: (III) Through edicts, the population must be warned that citizens who do not declare new cases - cases that occur in their houses and in other houses - within six hours will be prosecuted.

(IX) Meetings, dances and entertainments are strictly forbidden.

(XXII) The pharmacists must provide the poorest with the necessary treatments. A list of the citizens must be kept to distinguish between the poorer and the richer. The richer will pay for their treatments and the city government will pay for the paupers.

(XXXIII) It is highly recommended to be careful when shaking hands.

(XXXIV) All citizens are compelled not to leave their houses. Only one member per household is allowed to go out for shopping.

(XXXVI) People allowed to go out must bear with them a cane measuring 6 feet long. It is mandatory that people keep this distance from one another.

(XXXVIII) A large rail (parabanda) must be positioned in front of the counters in the shops in which meat, bread, wine and foodstuff are sold so that citizens will keep their distance from the counter itself.

These measures are from a manual (1588) published 433 years ago.

***** 

Alghero is a small town on the island of Sardinia, in Italy. In November 1582, a sailor arriving from Marseille imported plague from France. The disease was known as Buboes that affected the groin area. Alghero had Morbers, plague guardians, to check outsiders at the borders and stop them if they showed symptoms. This French sailor escaped scrutiny, became ill and died, but not before starting an epidemic.

This was much before modern science; diseases were still considered a divine punishment. They were caused by “bad air” (mal aria) and vinegar was the sole antiseptic. Plague treatments ranged from bathing in one’s urine (disgusting), to drawing the poison out of buboes by rubbing that part with the rump of a live chicken (absurd).

Against this background, appeared Quinto Tiberio Angelerio, a 50 year old doctor who had studied abroad. Fortunately, he was fresh from Sicily, which had experienced its own plague epidemic in 1575.

Angelerio took charge and set up a triple sanitary cordon around the city walls. The measures suggested by him: no handshakes, 6 foot distance, cancellation of all entertainment made him so unpopular; people wanted to lynch him. However, as more and more people died, his authority came to be accepted. People began self-isolating for forty days. (Quarantine comes from quaranta giorni, meaning forty days in Italian).

Some Italians secretly visited the houses of the infected, to meet friends, play the guitar and drink together. They were duly prosecuted.

*****

Angelerio also passed a decree specifying the eligibility of the gravediggers. Only those who had already contracted and survived the plague qualified. Theirs was a high risk job because they would transport confessional booths to the bedsides of dying patients, and deal with the dead bodies. Angelerio was ahead of his time, because the concept of immunity was not yet known.

A plague hospital, lazaretto, to isolate infected patients was an Italian concept. They were built all over Sardinia. Part-hospital, part-prison, patients were usually taken there by the city’s plague guardians.

Angelerio made certain the lazarettos in Alghero were efficient and humane. The plague guardians had to record everything that came in and went out – beds, furniture and food. The lazarettos were free for the poorest. Orphaned babies without a wet nurse were bottle-fed with goat milk. Goats were allowed to roam freely within the complex.

*****

The outbreak in Anghero lasted eight months, and then there was no epidemic for the next sixty years. When the next plague happened, the first thing that was referred to was Angelerio’s manual. (He had died in 1617). During the 1652 outbreak, the island followed to the letter his instructions, including the 6 feet social distancing. (I recommend reading the 57 instructions from his book).

Recent research suggests that 6 feet is indeed safer than three or four feet.

Ravi 

Sunday, May 23, 2021

Corona Daily 084: Crew Change Crisis


Ordering online on Amazon has become so easy. Few people realize that most things we order sit in a container on a ship at some point.

The Pandemic brought to a near halt all passenger cruises. But cargo, oil, component parts, food and finished goods must still be transported by ships. 90% of the world’s goods are transported by water. Seafarers’ work is demanding, working hours are long and irregular.  To avoid a burnout, they usually work in months-on, months-off rotation. In March 2020, shipping ports and airports closed. Shipping companies stopped shore leave for crews. Naval orders prevented military and civilian sailors from leaving the ships. Some are stuck for as long as 20 months, though 11 months is the maximum allowed by the Maritime Labour Convention. Seafarers stranded at home don’t earn anything. At the peak of the crisis, 400,000 seafarers were stranded. Today, that number is still as high as 200,000.

The situation may get worse. Most sailors have no access to vaccines due to the logistical challenges.

*****

In the maritime industry, licences and certifications are critical. The education and updating include in-person instruction and on-the-job training with equipment. But all classroom training has stopped for over a year now. Without proper certification, workers can’t get new jobs; no new cadets can be recruited. A chief mate can’t become a captain, and a second engineer can’t be promoted to the post of a first engineer.

It is estimated it may take five years to get back to the normal cycle. My next-door neighbor in Bombay, 61, an engineer who was scheduled to sail on an oil tanker, opted to retire instead once the pandemic began. Such unplanned retirements are aggravating the situation.                

Extended time on vessels causes worsening fatigue. Human errors induced by fatigue are a contributing factor in 75%-96% of marine accidents. A single mistake or accident can have a domino effect throughout the global supply chain. The Taiwanese Ship Ever Given that accidentally blockaded the Suez Canal delayed roughly $10 billion a day of trade for moving oil and manufactured goods.

*****

In numerous incidents, mariners suffering medical emergencies onboard were unable to go ashore for vital treatment. In January this year, a Greek captain tried to obtain medical care for a crew member off the coast of China. The captain spent hours negotiating with the port authorities to take the man to a Chinese hospital. He failed. The ill man was a Chinese citizen.

“We are spending our lives here.” The Greek captain said in a video. “We’re all prisoners and our freedom is sacrificed in order to maintain worldwide trading.”

The UN requested world governments to designate seafarers and other marine personnel as “essential workers”. Sadly, 118 out of 174 countries haven’t done so. This is another reason there has been no effort to vaccinate them.

Shortages of crew and cost-cutting have meant that the ship is usually very tightly crewed. There are no reserves for any position, and those working overwork. If the cook falls sick, crew must still eat, and no matter how many people are unwell, someone must stand watch. If there is a case or an outbreak, the ship will be out of commission at least for two weeks.

Pre-pandemic, the global supply chains also try the “just-in-time” principle for cost efficiency. A ship stopping for two weeks can stop several factories at the destination.    

*****

Major shipping lines have tried to increase the internet bandwidth on ships to allow sailors to connect with their families easily. Maersk and CMA CGM have chartered flights to change crews.                                      

USA or Britain getting out of the pandemic is no comfort for the seafarers. They must have restriction-free situations at the starting point, transit ports and the destination. The Pandemic is over for the shipping industry only once the whole world is free of coronavirus.

Until then, what you order on Amazon may occasionally be delayed. Unless the world unites to resolve the crew change crisis, it is likely the prices for many goods carried on ships will zoom upwards. That is when this crisis will be truly appreciated.

Ravi                                                                                                                 

Saturday, May 22, 2021

Corona Daily 085: Copycat


India’s vaccination drive is in a mess. At least 130 million Indians are waiting for their second dose; their appointments cancelled, and promises broken. The initial gap of 28 days between two doses was extended to 45 days, and now 84 days. Even while India didn’t have enough vaccines for 45+, it made them available for everyone above 18.   

 Today, the executive director of the Serum Institute, the world’s largest vaccine maker, said the government (euphemism for Modi) widened the vaccination drive without considering stock levels or the WHO guidelines.

I will try to offer a logical explanation for PM Modi’s actions.

***** 

Last year, on 19 March, Narendra Modi, in his address to the nation asked Indians to applaud the doctors and nurses. On 22 March, everyone should come out of the house, clap, bang pots and pans, ring bells at 5 pm, for 5 minutes. It was a passionate speech. Modi is an orator and actor of a high caliber. If instead of politics, he had joined the film industry, both Bollywood and India would have greatly benefited.

Neither in his address nor Twitter was there any hint that something similar had been done before. Millions of Indians still believe this was Modi’s original initiative.

In Europe, Italy started with pots, accordions, songs and clapping. Paris followed. Before Modi suggested it, the idea was implemented in Wuhan, Istanbul, Atlanta, and Buenos Aires. Of course, Modi was not obliged to mention the other places. But it showed the man was capable of copy-pasting ideas without acknowledging their origin.

It is noteworthy that in all other places, even in Wuhan, the clapping and pot banging was done by the people spontaneously, no government was involved.

*****

On 27 March, 2020, the USA passed the CARES Act, a revolutionary stimulus bill that offered $2.2 trillion for the survival of Americans and the US economy during the pandemic. This unprecedented Act contributed to the development of vaccines.

On the same day, 27 March, 2020, India launched the PM CARES fund. There were certain differences. Before Trump’s signing the CARES act into a law, the US Congress had to debate and pass it. That is a lengthy, bureaucratic and inefficient process. Narendra Modi simply launched the fund, which was private, with no public debate before or scrutiny after. A narcissistic prefix was added to let Indians know who cares about them. America’s CARES act package was almost 70% of India’s GDP, it was impossible to match it. Instead, the PM CARES fund decided to collect money from the people. $400 million were collected.

Serum institute’s owner had asked for $10 billion. PM CARES allocated $14 million for vaccine development.

Most importantly, India managed to launch its own CARES on the same day as the USA. Since America first debated the bill, it gave Modi enough time to synchronise the date. Just like a smart copying student changes little bits here and there, the full form was altered. USA’s CARES stood for Coronavirus Aid, Relief, and Economic Security. Modi’s CARES meant Citizen Assistance and Relief in Emergency Situations.

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There was no plan to vaccinate people younger than 45. But then on 11 March, Joe Biden made an announcement: As part of America’s war-time effort, he would make every adult (18+) in the US eligible for vaccination no later than 1 May.

Modi was busy addressing election rallies in front of record crowds. He hurriedly noted the news. At the first opportunity, back in office, he announced India would make every 18+ Indian eligible for vaccination from 1 May. Vaccine shortage didn’t matter. Once again, Modi managed to match America word for word, date for date.

If you think these are mere coincidences, remember Modi is fiercely competitive. In 2016, with shocking abruptness, he made 86% of the Indian currency illegal. He ensured the timing synchronized with the US presidential election. For the entire day, Indian TV channels were focused on the loss of currency rather than loss of Hillary.

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In academic institutions, the plagiarizing student gets disciplined. Here, Indians are being punished for copy-pasting by the man supposed to govern them.

Ravi 

Friday, May 21, 2021

Corona Daily 086: Miscarrying Cows


In the beginning of the twentieth century, USA had an epidemic among cows. A bacterial infection called brucellosis was spreading through the cattle, causing spontaneous miscarriages, known as “contagious abortion”. By the 1910s, the miscarriages threatened livestock across the USA.

Worried about the disease, farmers would kill the diseased animals, to try to eradicate bacteria from their herds. George Potter, a vet from Kansas had an epiphany: a cow getting brucellosis may lose its calf, but at the same time acquire immunity to the disease. An immune cow was more valuable than an uninfected one.

In a 1918 article in the Lancet, Potter compared the miscarriage disease to a fire, which unless new fuel is constantly added, dies down. “Herd immunity is developed, thereby retaining the immune cows, raising the calves and avoiding the introduction of foreign cattle. This was the first known use of the term “Herd Immunity”.

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In the 1920s this concept made some scientists curious. They began deliberately infecting mice to see how the disease spread through their colonies. They discovered that above a certain threshold, the infection couldn’t find new hosts, and stopped spreading.

In 1923, a British pathologist Sheldon Dudley studied a diphtheria outbreak at a crowded navy school. One thousand children of naval officers ate together in a dining hall, and slept in cramped military-style barracks. Dudley found that every time new students joined the school, the diphtheria bacteria would attack the newcomers, and an outbreak would start again. In 1924, Dudley applied, possibly for the first time, the term “herd immunity” to humans.

Now in covid times, a semi-literate person uses the expression. Equating us to cattle may sound offensive. But the term’s origin was in the herd of miscarrying cows.

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While Dudley was studying diphtheria, a diphtheria vaccine was developed. He began wondering: What is the best way to reach herd immunity: natural exposure or vaccination?

Last year, several heads of states thought of reaching herd immunity through natural exposure. To be fair, there were no vaccines then. Johnson started with it in the UK. Trump’s advisor Scott Atlas, who called himself anti-Dr Fauci, recommended it. (Trump was so unengaged; he often called it herd mentality). Sweden took it as an official state policy. And Russia adopted it without an official pronouncement.

All these nations were heavily punished. The UK and USA had to rethink. Sweden acknowledged the unnecessary loss of thousands. Russia has unofficially lost more than half a million to covid.

It is possible to opt for mass natural exposure if the virus is not deadly. Without vaccinations, Indians develop herd immunity against the flu every season. Because flu is not so deadly. Covid virus kills and maims. Such a plan inevitably leads to catastrophic loss of lives and suffering. We usually look at the death count. But many infected people suffer long covid, with damaged organs. They may take years to recover, or not recover at all.

Herd immunity against covid through natural exposure is rejected by scientists as unrealistic and unethical. Vaccination is the only ethical road.

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The formula for calculating the required herd immunity percentage is 1- (1/R0), which in simple language means the more transmissible the virus, the higher is the %. For example, measles, an extremely infectious disease, has an R0 between 12 and 18, which translates into a herd immunity threshold of 92-94% of the population.

Looking at this number on a national basis is a mistake. In large countries like the USA or India, some places may be vaccinated enough to reach immunity, but less vaccinated pockets may still be vulnerable.

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Finally, when the USA or UK currently say their R0 (spreading rate) is low, it is low because of the lockdowns, masks, handwashing, and distancing. When human behavior changes; people start throwing masks away, and hugging; the R0 can go up, and with it the herd immunity % required shoots up. Coming months will show whether the joy of these nations was premature.

This is why fully vaccinating an entire nation and the entire world may be the only effective way to achieve herd immunity.

Ravi