Eighteen months after its birth, there appears to be a consensus among scientists that the origin of covid-19 virus was the horseshoe bat. The virus spilled over into humans either directly, or more likely via another animal. The genome analysis suggests it could be a cross between a bat virus and say a pangolin virus, with some additional genetic sequence (called furin cleavage site) that makes it far more infectious for humans.
Such blending and spicing up can be done in labs. In
2015, Dr Shi’s team from WIV created a chimera from a bat coronavirus and a
mouse coronavirus that was able to replicate efficiently in human airway cells.
Those suspecting a lab leak suggest the engineering of the furin cleavage site
could have been the product of WIV.
However, most scientists believe such engineering is
more likely to happen in nature. Nature is the greatest designer.
The lab leak theory neither insists on a Wuhan lab designing
the covid-19 virus, nor deliberately using it as a bio-weapon. The naturally
created virus could accidentally slip from a lab through negligence, accident
or sheer bad luck. Crashing of a Petri dish is not required. An infected bat, brought
in for research, can transmit the virus to a lab employee, and start a global
pandemic.
*****
In this mystery, where millions are killed, certain
suppression of data raises doubts. China has the key epidemiological data on
the first 174 covid patients in December 2019. The authorities refused to share
it with the WHO delegation. Such data is critical for investigation, and can
clearly tilt the balance towards one of the hypotheses.
China is in a difficult situation. If they keep the
data secret, they will be assumed guilty. If they share it, who knows what will
come out.
They have instead opted for whataboutism. A hawkish
Chinese ministry spokesman has demanded the USA opens up its Fort Detrick (a US lab established to
develop bio-weapons in the past, now runs a biological defence program) for
international scrutiny. The biologist Dr Daszak reminds us that China is a
sovereign country. Why should it open up its lab records to outsiders? Daszak
must ask the coronavirus if it is aware of the concept of a country’s sovereignty.
*****
The stated objective of the virus re-engineering
research (gain of function) was to prevent pandemics. The irony is that such
research has not prevented, but may have caused the pandemic. Neither did the
WIV manage to create covid medicines or vaccines as promised in its agenda.
Countries are now competing for virology research. There
is no global authority or international treaty that sanctions such labs. USA
already has more than a dozen BSL-4 labs, and more are planned. After the
pandemic, more scientists will be keen to research dangerous viruses. That will
mean more researchers going to the caves, coming into contact with BATS and
other animal reservoirs of viruses, collecting samples, working on them in
labs, upgrading them to make them potent killers, and in this entire process
leaking them through accident or negligence.
The existence of such viruses is itself a major
threat. Despite repeated requests to destroy them, a collection of live smallpox
viruses is stubbornly held at Koltsovo (Russia), and Atlanta (USA). It just
needs a single madman to use them. Both USA and Russia have shown capability of
having madmen at the helm.
China should use this as a negotiation tool. To open
up their records, they can insist on an international audit of all such labs in
the world. That would be fair. Any lab leak can start another pandemic. An
international treaty exercising strict controls and scrutiny over all bio-labs
is essential. As critical as control over nuclear installations. Pandemics may
be a greater threat than nuclear warfare. In the name of science, researchers
can’t make the world a more vulnerable place. The gain of function research to
make natural viruses more vicious should be banned. The smallpox viruses in
Russia and USA must be destroyed.
If such bargaining results in worldwide bio-safety lab
reforms, China may be forgiven even if the lab leak theory proves correct.
Ravi
काय खरं नि काय खोटं
ReplyDeleteimmaculate analysis and conclusion
ReplyDeletelobh...
If you were a betting man, given everything you've analyzed so far, would you put your money on it being Natural or Manmade ? I think you're leaning towards the latter but just wanted to confirm...
ReplyDeleteWell Apurv, I am a betting man.
DeleteI would slightly tweak your question. Both natural and manmade viruses can leak from a lab. Based on what the scientists are saying, the virus itself appears to be natural, rather than man-made. The several mutations over the last year can be offered as evidence that nature can keep making a virus more transmissible or lethal.
As I mentioned in the article, it is possible a bat infected with SARS-CoV-2 was in some Wuhan lab. The infected bat could have been picked up from a Yunnan cave several months ago. At a lab it could have infected a researcher, as a result of negligence, even temporary negligence, like we pulling our masks down through fatigue. Something similar strikes me as the most probable scenario.
All this conjecture is based on the data available today.
So, not necessarily man-made, but through a lab leak. In other words, with no labs in Wuhan, and no coronavirus research in Wuhan, this pandemic may not have happened.
Sounds frightening simple, but deadly
ReplyDelete